Coagulation Profile (PT, INR, aPTT)

The Coagulation Profile is a set of blood tests used to evaluate how well and how quickly your blood clots. It includes:

• PT (Prothrombin Time): Measures the time it takes for blood to clot via the extrinsic and common coagulation pathways.

• INR (International Normalized Ratio): A standardized version of PT, especially useful for those on oral anticoagulant therapy (e.g., warfarin).

• aPTT (Activated Partial Thromboplastin Time): Assesses the intrinsic and common pathways of clot formation.

These tests are crucial for diagnosing bleeding disorders, monitoring anticoagulant therapy, and assessing liver function or clotting factor deficiencies.

🔬 When Is It Needed?

• Before surgery to check for bleeding risk

• Monitoring blood thinners (warfarin, heparin)

• Investigating symptoms like frequent nosebleeds, easy bruising, or heavy menstrual bleeding

• Diagnosing liver disease, vitamin K deficiency, or inherited clotting disorders

🧪 Sample Type:

• Blood sample from a vein

• Usually no fasting required, but inform your doctor about any medications

⚠️ Abnormal Results May Indicate:

Prolonged Clotting Time:

• Liver disease

• Vitamin K deficiency

• Anticoagulant therapy (warfarin/heparin)

• Hemophilia or clotting factor deficiencies

• DIC (Disseminated Intravascular Coagulation)

Shortened Clotting Time:

• High risk of clot formation (thrombosis)

• Certain inflammatory or cancerous conditions

✅ Key Benefits:

• Prevents bleeding complications during surgery

• Monitors anticoagulant therapy

• Helps diagnose serious blood and liver disorders

• Identifies genetic or acquired clotting abnormalities

The Coagulation Profile test is a vital diagnostic tool to ensure blood clotting is balanced, helping to avoid both excessive bleeding and dangerous clot formation.